Papers include political correspondence with various supporters discussing political prospects and issues; business correspondence re Calhoun's planting and farming enterprises in S.C. and Alabama; his gold mining investment in Georgia; his interest in development and expansion of railroads; and family correspondence. Correspondents include: John B. Adger, J.E. Bonneau, Ker Boyce, Orestes A. Brownson, Andrew Pickens Calhoun, Anna Maria Calhoun, Cornelia Calhoun, Floride Calhoun, James Edward Calhoun (Colhoun), James Edward Calhoun, Jr., John C. Calhoun, Jr., Margaret M. Calhoun, Marie E. Calhoun, Patrick Calhoun, William L. Calhoun, Farish Carter, Thomas Green Clemson, Richard K. Cralle, Tomlinson Fort, Henry Gourdin, Benjamin E. Green, Duff Green, Samuel D. Ingham, Andrew Jackson, Thomas Jefferson, David Johnson, James MacBride, Virgil Maxcy, Matthew McDonald, George McDuffie, James Monroe, Patrick Noble, Miles M. Norton, Andrew Pickens, Jr., Francis W. Pickens, Condy Raguet, Robert Barnwell Rhett, James A. Seddon, Joseph J. Singleton, Micah Sterling, A.G. Summer, William Summer, Decius Wadsworth, William L. Yancey, and others. Places represented include the S.C. locales of Abbeville, Charleston, Columbia, Edgefield, Fort Hill, Pendleton, South Carolina College, and Terrysville; other places represented include Alabama (Demopolis, Marengo County, Mobile, Perry County, Selma, and Union Town); Arkansas (Fort Towson); Washington (D.C.); Georgia (Dahlonega); Maryland (Baltimore); New York (Watertown and West Point); Pennsylvania (New Hope and Philadelphia); University of Virginia; and Brussels (Belgium).